After a 800 round trip, by the end, I had terrible pain in my sitz bones. Before the trip, I had experienced the same pain while riding on 100 mile trips. As an effort, I have modified the stock pillow top seat by removing the soft foam and carving the harder foam to better fit. Also I used an airhawk pad on the trip. But both of these "solutions" have not helped.
Any other suggestions, would greatly be appreciated.